Incumbent will be responsible for testing samples for early stage (Phase I) clinical studies as a member of the Clinical Immune Monitoring Group. The candidate will also be responsible for maintenance and upkeep of multiple flow cytometers. The role is focused on flow cytometry assays but also includes performance of other cell-based assays on clinical samples. The role requires an in-depth technical knowledge of multi-parameter flow cytometry using the Becton Dickenson platform and good understanding of relevant software including FACS Diva and FlowJo. Experience of working in a BSL2 level tissue culture laboratory is required, as well as an understanding of cellular immunology and the key assay platforms of flow cytometry and ELISPOT. The role requires good analytical skills, attention to detail and the ability to clearly document and present complex biological data. Incumbent is required to multitask and work as part of a team that is required to meet business-critical deadlines.

Role responsibilities:

• Conduct clinical flow cytometry assays in accordance with GCLP requirements.
• Conduct clinical ELISPOT assays in accordance with GCLP requirements.
• Analyze, document and report experimental data in accordance with Pfizer/GCLP requirements.
• Support the efficient and compliant operation of the laboratory by developing appropriate processes and standard operating procedures, working with others to operate the laboratory, and by becoming an expert user in key areas of operation (such as LIMS and GDMS).
• Assist in the sourcing and maintenance of reagents required to conduct clinical flow cytometry assays in a compliant manner.
• Maintain and build a broad knowledge of key assay platforms (including flow cytometry and ELISPOT assays) and the scientific rationale underpinning the assays through appropriate training and self-learning.

EEO & Employment Eligibility
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Sunshine Act

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