This is a temporary contractor assignment. The individual in this role will be employed by a third party, not by Genentech.

Job Knowledge & Scope
RMG, in the Cell Culture and Bioprocess Operations department, is responsible for providing support to pre-Early Stage Research to Early Development projects with high-throughput protein production from mammalian transient cultures. We are looking for a motivated candidate with cell culture and sterile technique experience to join our team to enable protein production at Genentech and help advance our portfolio.

Key Responsibilities

• Perform transient transfections in CHO and HEK293 cells in scales 1mL to 25L to support pipeline productions adhering to established protocols

• Maintain seed train cell cultures in bioreactors and shake flasks

• Operate liquid handlers - Tecan and Hamilton for automated processes

• Operate wave bag reactors for productions and cell maintenanceMaintain and troubleshoot key cell culture instruments such as Vi-Cell, Nova Flex2, Nova Flex,

• Cedex and bioreactors

• Participate in troubleshooting production or platform processes

• Participate in lab management and data management.

• Contribute to improving existing cell culture platforms and developing new platforms to

• deliver diverse protein and cellular reagents to enable a large number of research programs.

The candidate must be highly self-motivated, organized, detail oriented and responsive to feedback. The candidate is expected to precisely follow written procedures, practice sterile technique, demonstrate accurate documentation skills, and report deviations in a timely manner. They should be able to work independently within guidelines and policies, with minimal guidance.

Qualifications
Required:

• PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related fields

• Suspension adapted mammalian cell culture (CHO and/or HEK293)

• Excellent written and verbal communication skills, and have strong collaborative skills.

Preferred:

• State-of-the-art transient and stable protein expression experience

• Relevant bioreactor experience

• Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and

• Hamilton Microlab Star

• Knowledge of cell biology, cell engineering, molecular biology, recombinant protein

• purification and protein characterization is preferred

Please note:

• Relocation benefits are not available for this job posting.

• The expected pay rate for this position based on the primary location of South San Francisco, CA is $69 to $90 hourly. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.